Tuesday, July 7, 2009

Quick Quiz Question

What's your diagnosis? (Answer is posted in the comment section.)


Brian E. Moore, MD, MEd said...

Answer: If you had interpreted the photo as exhibiting bilateral globus pallidus necrosis, you might have guessed carbon monoxide poisoning as the answer. But, in that case, you would have been wrong. This is actually a case of Hallervorden-Spatz disease (also known as neurodegeneration with brain iron accumulation, type I or pantothenate kinase-associated neurodegeneration). The tell-tale sign of Hallervorden-Spatz in this gross photograph is the characteristic bilateral yellow-brown discoloration and atrophy of the globus pallidus.

jd said...


Brain Pathology's “Under your Microscope” Now Underway

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