Limb Apraxia in a case of corticobasal degeneration

This week I'll be doing a brain cutting on a patient with a clinical diagnosis of corticobasal degeneration. What made the clinical diagnosis a little easier in this case is the fact that the patient exhibited "alien limb" phenomenon of the left arm. Limb apraxia was also present. Apraxia is a disorder of skilled, learned, purposeful movement. CBD is is one of the few disorders in which limb apraxia can appear in the history (ie, patients are often aware of the apraxia).