I discuss issues pertaining to the practice of neuropathology -- including nervous system tumors, neuroanatomy, neurodegenerative disease, muscle and nerve disorders, ophthalmologic pathology, neuro trivia, neuropathology gossip, job listings and anything else that might be of interest to a blue-collar neuropathologist.
Friday, August 29, 2008
What's is meant by "luysian" in dentatorubral-pallidoluysian atrophy?
Dentatorubral-pallidoluysian atrophy is an autosomal dominant spinocerebellar ataxia which occurs most frequently among the Japanese. "Dentato" refers to the dentate nucleus of the cerebellum; and "rubral" alludes to the red nucleus. "Pallido" of course indicates the globus pallidus. But what does "luysian" refer to? I posed this question to the illustrious Dr. John Donahue (pictured), neuroanatomist extraordinaire, who reminded me that the subthalamic nucleus is also knows as the "Body of Luys" or "Corpus Luysii", named in honor of the noted French neurologist Jules Bernard Luys (1828–1897), who gave the first detailed description of this structure in the basal ganglia.
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WOOHOO!!! EGS was in the office when I said, "Let's see what's on the blog today," and this pops up! Thanks for the plug!
Dr. Moore, Welcome to the Springfield blogosphere. Actually, I've been reading your blog for quite some time, but thought this post would a good time to say something. I'm not sure why, though. Anyway, welcome.
Thanks, Marie. It's a pleasure to be in Springfield blogosphere. Keep reading, and I'll add your blog to me Google Reader to keep up with your posts as well. Thanks.
Here is a link to more information about the genetics of Dentatorubral-Pallidoluysian Atrophy that was prepared by our genetic counselor and which has links to some useful resources for those dealing with this condition: http://www.accessdna.com/condition/Dentatorubral-Pallidoluysian_Atrophy/681. There is also a phone number listed if you need to speak to a genetic counselor by phone. I hope it helps. Thanks, AccessDNA
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