Wednesday, January 18, 2017
Nice Example of STAT6 nuclear positivity in a WHO grade III Solitary Fibrous Tumor/Hemangiopericytoma
STAT6
immunostaining shows strong nuclear positivity among tumor cells, while the
cytoplasm is uniformly negative. STAT6
nuclear immunoreactivity has been reported as a surrogate marker for the
NAB2-STAT6 gene fusion, which is the defining driver mutation of solitary
fibrous tumor/hemangiopericytoma.
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