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| Christian Davidson, MD |
Dr. Christian Davidson, director of neuropathology at the Robert Wood Johnson University Hospital in New Jersey, provides today's blog post:
A 30-year-old man presented with bitemporal hemianopsia and
a 3.0 cm pituitary mass was discovered upon MRI. His IGF-1 was elevated to 900,
but he had no signs of acromegaly. A smear of tissue sent for frozen section
evaluation (see below) revealed that most cells had round,
eosinophilic, perinuclear inclusions suggestive of fibrous bodies (some examples are circled). Dot-like
CAM5.2 immunostain (not shown) confirmed my smear-based diagnostic suspicion.
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