|Photo courtesy of Shellie Sherrod|
"If you were constructing a panel of eight biomarkers there were well-established prognostic/predictive markers for CNS neoplasms, what markers would be included? Note: this is not for diagnosis, but for predicting behavior and should include adult and pediatric brain tumors and can include immunohistochemical and molecular tests."
Thanks in advance for providing your opinion in the comments section.
ATRX, p53, IDH1, ki67
1. A surgeon who can hit the lesion
2. Deeper levels (H&E) to find mitoses &/or vascular proliferation
3. Sending the case to a real tumor neuropathologist
Søland TM, Brusevold IJ. Prognostic molecular markers in cancer - quo vadis?
Histopathology 2013, 63, 297–308. DOI: 10.1111/his.12184
Great reference. Great comment. So true.
I love Agent 86.
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