Photograph of Subthalamic Cavitation in Leigh's disease

In response to a post I wrote last week (January 7) on Leigh's disease, our loyal but anonymous reader Gliageek, also know as Agent86, sent me a link to FrontalCortex.com for photographs of the cavitatary devastation perpetrated by Leigh's disease. An example from that fine website is shown above, which depicts cavitation of the subthalmic region in a coronal brain autopsy section of a patient who suffered from Leigh's. To me, the most striking aspect of this disease is the exquisite symmetry of the lesions it leaves behind.