Monday, August 13, 2018
Salzmann nodular degeneration of the cornea
Salzmann nodular degeneration was once called Salzmann nodular dystrophy. It is now recognized that this typically unilateral disorder is not heritable and is best classiﬁd as a secondary degenerative process of uncertain cause. Clinically, the corneal epithelium is focally elevated by white mounds of dense collagenous connective tissue. Salzmann nodular degeneration resembles a massive focal pannus histopathologically. Mounds of relatively acellular hyaline connective tissue elevate the corneal epithelium anterior to the plane of Bowman membrane, which may be destroyed.
Source: Reference: Eagle, Ralph C. Eye Pathology: An Atlas and Text [2nd edition] page 86.