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40 year old female with progressive headaches over 6-8
months. MRI showed a large cystic and solid mass, favored to be extra-axial and
arising from the anterior skull base just left of midline with possible dural
attachment. Sections showed a densely cellular mass arranged in a mostly
haphazard, slightly fascicular pattern. Alternating hypercellular and
hypocellular areas were seen. Tumor cells were ovoid to spindle shaped with
scant eosinophilic cytoplasm. No eosinophilic bands of wire-like collagen were
noted, and only focal staghorn-like vasculature was identified. Only up to 3
mitotic figures were enumerated in 10 hpf counts. No necrosis was identified. You can see the diagnosis in the comment section after considering the photographs below:
The American Association of Neuropathologists has released the cases for the 2017 Diagnostic Slide Session, which will be held at the association's annual meeting on Saturday, June 10 from 8 to 11 pm. The session, which will be moderated by Drs. Caterina Giannini Rebecca D. Folkerth, focuses on a discussion of 10 cases submitted by members from far and wide.