Thursday, August 17, 2017

Best Post of June 2017: Additional photograph of remarkable CNS/PNS dissection

The next in our "Best of the Month" series is from June 12, 2017:

Taken by our staff photographer, Lisa Litzenberger.

Tuesday, August 8, 2017

College of American Pathologists Neuropathology Committee met in Monterey, CA this past weekend

The College of American Pathologists Neuropathology (CAP-NP) Committee met in Monterey, CA this past weekend.  We are making plans for our next SAM-eligible educational product that will, among on things, update you on the latest World Health Organization system of pituitary adenoma classification. After a long day at work on the CAP-NP educational product, committee members retired to a nearby restaurant where this picture was snapped:

Some of the CAP Neuropathology Committee members (left to right, in the foreground)" Brett Harris, Andrea Weins, Areli Cuevas-Ocampo, Matt Scheiderjan (standing), Eyas Hattab (seated), and Rania Hattab (wife of Dr. Eyas Hattab)

Friday, July 14, 2017

Best Post of May 2017 - Guest Post: A Case from the Hawkeye State

The next in our "Best of the Month" series is from May 19, 2017:

From the illustrious Dr. Karra Jones of the University of Iowa:

Karra Jones, MD, PhD
40 year old female with progressive headaches over 6-8 months. MRI showed a large cystic and solid mass, favored to be extra-axial and arising from the anterior skull base just left of midline with possible dural attachment. Sections showed a densely cellular mass arranged in a mostly haphazard, slightly fascicular pattern. Alternating hypercellular and hypocellular areas were seen. Tumor cells were ovoid to spindle shaped with scant eosinophilic cytoplasm. No eosinophilic bands of wire-like collagen were noted, and only focal staghorn-like vasculature was identified. Only up to 3 mitotic figures were enumerated in 10 hpf counts. No necrosis was identified. You can see the diagnosis in the comment section after considering the photographs below:

Axial MRI T1 Post-Contrast




Wednesday, July 5, 2017

Best Post of April 2017: Screenshots of the surgical neuropathology volume of the Johns Hopkins Atlases of Pathology

The next in our "Best of the Month" series is from April 6, 2017:

A month ago I put up a post regarding the release of Volume 3 of the Johns Hopkins Atlases of Pathology for the iPad. This app only costs $4.99 .  Here are some screenshots of the app provided to me by series editor Toby Cornish, MD, PhD:

Thursday, June 22, 2017

Which subtypes of pituitary adenoma must you be aware of as tending to be more clinically agressive?

Certain subtypes of pituitary adenoma have been shown to be more clinically aggressive in that they tend to be more invasive, have earlier recurrence, and are more resistant to treatment. The following adenoma subtypes are recognized as having a more aggressive clinical behavior:

- Acidophil stem cell adenoma
- Crooke cell adenoma
- Lactotroph adenoma when occurring in men
- Pit-1 positive plurihormonal adenoma
- Sparsely granulated somatotroph adenoma
- Silent corticotroph adenoma

Thanks to Dr. Bea Lopes of the University of Virginia for consulting on the compilation of list!

Best Post of March 2017: Why is the confluence of the cerebral venous sinuses called the "torcula"?

The next in our "Best of the Month" series is from March 3, 2017:

Torcula is derived from a Latin word meaning to “twist” and was also used to refer to a wine press. Within the cranium the venous sinuses come together at the back of the skull in a structure called the confluence of the sinuses. This cavity has four large veins radiating from it, supposedly resembling the spigots that pour dark purple juice out of the four sides of the ancient wine press used to squeeze grapes with a handled screw on the top. The same stem is found in common words such as torture and tortuous.

Monday, June 12, 2017

Additional photograph of remarkable CNS/PNS dissection

I wanted to share this additional photo related to the last post. It was taken by our staff photographer, Lisa Litzenberger.