Thursday, April 3, 2008

First report of a primary intracerebral angiomatoid fibrous histiocytoma

The esteemed Dr. Chad DeFrain provided me with a case report from the American Journal of Surgical Pathology (2008;32:478–484) which describes the first reported case of a primary intracerebral angiomatoid fibrous histiocytoma. The relatively large tumor was located in the left occipital lobe. A team led by Dr. Arie Perry at Washington University in St. Louis describes the tumor as having a unique clear cell sarcoma-like gene fusion transcript, t(12;22). The authors conclude: "Although AFHs are usually associated with a favorable prognosis, the impact of this tumor’s atypical cerebral location and unique molecular features are unclear."

1 comment:

jd said...

A zebra I'll probably not remember long-term. I'll give it to one of my general pathology colleagues for consultation.