Friday, November 9, 2007

JNEN article on synucleinopathies

In the introduction to the article cited yesterday, the authors describe two subtypes of multiple system atrophy (MSA-P and MSA-C). What about the type in which primary autonomic failure is the predominant presentation? Does the dysautonomic subtype (formerly known as Shy-Drager syndrome) have a specific MSA subtype designation? And, where would one find neuropathologic evidence of disease in that subtype? That information is missing from the introduction. Given that this is supposed to be a review article, I would think that that aspect of MSA would be addressed.

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