Tuesday, November 20, 2007

CNS Whipple disease

Somebody asked me the other day about CNS Whipple disease. I said that I thought it was an instestinal infection and didn't think it had a CNS manifestation. I thought wrong. Caused by Tropheryma whippelii, a gram positive intracellular actinomycete, Whipple disease of the CNS can cause various symptoms, including ophthalmoplegia.

1 comment:

JD said...

True. I had a case that I thought might be CNS Whipple, but it ended up not being so.