Tuesday, November 20, 2007
CNS Whipple disease
Somebody asked me the other day about CNS Whipple disease. I said that I thought it was an instestinal infection and didn't think it had a CNS manifestation. I thought wrong. Caused by Tropheryma whippelii, a gram positive intracellular actinomycete, Whipple disease of the CNS can cause various symptoms, including ophthalmoplegia.