A Rosenthal fiber in pilocytic astrocytoma |
"In 1898, the
German pathologist Werner Rosenthal noted elongated inclusions
within the gliotic edge of a syringeal cavity of an ependymoma. Assigned
to write the case report by a senior mentor while serving as a “first
assistant” at the University of Erlangen, Rosenthal colorfully described these
inclusions as a “glossy formation of little bulbs or wavy sausages with one
thick and one pointed end.”…. His supposition that they were
related to glial fibers would prove surprisingly insightful. Not until some 20
years later did Bielschowsky and Unger use the term 'Rosenthal fibers' when
describing structures in the gliotic capsule of a cystic teratoid tumor."
Quoted from: F.J. Wippold, A. Perry and J. Lennerz.
Neuropathology for the Neuroradiologist: Rosenthal Fibers. American Journal of
Neuroradiology May 2006, 27 (5) 958-961.
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