Friday, May 19, 2017

Guest Post: A Case From the Hawkeye State

From the illustrious Dr. Karra Jones of the University of Iowa:

Karra Jones, MD, PhD
40 year old female with progressive headaches over 6-8 months. MRI showed a large cystic and solid mass, favored to be extra-axial and arising from the anterior skull base just left of midline with possible dural attachment. Sections showed a densely cellular mass arranged in a mostly haphazard, slightly fascicular pattern. Alternating hypercellular and hypocellular areas were seen. Tumor cells were ovoid to spindle shaped with scant eosinophilic cytoplasm. No eosinophilic bands of wire-like collagen were noted, and only focal staghorn-like vasculature was identified. Only up to 3 mitotic figures were enumerated in 10 hpf counts. No necrosis was identified. You can see the diagnosis in the comment section after considering the photographs below:

Axial MRI T1 Post-Contrast





CD34


CD34

STAT6

1 comment:

Brian E. Moore, MD, MEd said...

Solitary Fibrous Tumor/Hemangiopericytoma, WHO grade II


This is a tumor with a hemangiopericytoma morphologic pattern, but with fewer than 5 mitotic figures/10 hpf and without necrosis.