Guest Post: A Case From the Hawkeye State

From the illustrious Dr. Karra Jones of the University of Iowa:

Karra Jones, MD, PhD

40 year old female with progressive headaches over 6-8 months. MRI showed a large cystic and solid mass, favored to be extra-axial and arising from the anterior skull base just left of midline with possible dural attachment. Sections showed a densely cellular mass arranged in a mostly haphazard, slightly fascicular pattern. Alternating hypercellular and hypocellular areas were seen. Tumor cells were ovoid to spindle shaped with scant eosinophilic cytoplasm. No eosinophilic bands of wire-like collagen were noted, and only focal staghorn-like vasculature was identified. Only up to 3 mitotic figures were enumerated in 10 hpf counts. No necrosis was identified. You can see the diagnosis in the comment section after considering the photographs below:

Axial MRI T1 Post-Contrast

CD34

CD34

STAT6

Best Post of January 2017: Corneal ulceration secondary to Candidal keratitis

The next in our "Best of the Month" Series is from January 20, 2017. A good photomicrograph is worth a thousand words.

GMS stain highlights fungal forms in the corneal stroma

Registration still open for annual meeting of the American Association of Neuropathologists

https://aanp.memberclicks.net/2017_AANP_Annual_Meeting_FINAL#/

Diagnostic Slide Session cases have been released by AANP

The American Association of Neuropathologists has released the cases for the 2017 Diagnostic Slide Session, which will be held at the association's annual meeting on Saturday, June 10 from 8 to 11 pm. The session, which will be moderated by Drs. Caterina Giannini Rebecca D. Folkerth, focuses on a discussion of 10 cases submitted by members from far and wide.