|Craig Horbinski, MD, PhD.
Monday, June 16, 2014
Horbinski Group develops online tool to estimate likelihood of IDH1/2 mutation in a glioma
The illustrious Craig Horbinski, MD, PhD wrote in to share a link to an online tool which his team developed which helps triage brain tumor cases that might benefit from additional molecular testing. Here's what the University of Kentucky neuropathologist had to say about this new website: "We have developed an online-based tool to provide a statistical estimate of the likelihood of an IDH1/2 mutation in a glioma, basedon a few easily-obtained parameters. Several variables like patient age, WHO grade, etc. are well-known to correlate with mutations, but no formula has yet been developed that synthesizes those variables into one unified probability score. An added feature is that it generates separate scores if no testing has been done at all, and if R132H IDH1 immunostain was done but is negative. Hopefully this will help pathologists and investigators better triage cases that would benefit from additional testing, both in clinical and in research endeavors."
A neuropathology colleague in Toronto (Dr. Phedias Diamandis) is developing some amazing AI-based tools for pathology and academia. He hel...
Remarkable en bloc dissection of human central and peripheral nervous system accomplished at University of ColoradoShannon Curran, MS with her dissection Shannon Curran, a graduate student in the Modern Human Anatomy Program at the University of Co...
The meticulously extracted nervous system of a 19th-century woman on display at Hahnemann Medical CollegeLast summer I put up a post about a remarkable whole nervous system dissection that was carried out at the University of Colorado School of ...