Sunday, March 22, 2009

More on neurofibrillary tangles in teenagers

In a recent post, I presented a case of a teenager with neurofibrillary tangles. The tangles were present in cortex adjacent to meningioangiomatosis. Dr. Doug C. Miller wrote in that there are other circumstances in which you might see such tangles in a teen. He writes: "Other possibilities you might think about in a teenager with tangles (before you look at the slides): SSPE in which affected brain can have tangles; and gangliogliomas, as rare cases in which the tumor neurons may have tangles are described." Thanks, Doug!

2 comments:

jd said...

Tubers in tuberous sclerosis can have abnormal, tangle-containing cells as well.

Dr. Bob said...

how do these tangles compare to the NFT in Alzheimer disease? Do they show the same abnormalities that are found in NFT?