tag:blogger.com,1999:blog-5424255638293718915.post4238234293437254691..comments2024-03-18T01:10:51.745-05:00Comments on neuropathology blog: Study sheds light on Huntington disease with implications for other neurodegenerative disordersBrian E. Moore, MD, MEdhttp://www.blogger.com/profile/17503916201692804693noreply@blogger.comBlogger2125tag:blogger.com,1999:blog-5424255638293718915.post-64269511209184687292009-06-09T10:26:39.359-05:002009-06-09T10:26:39.359-05:00I have not read the study in Science yet, so this ...I have not read the study in Science yet, so this may be premature. Dr Snyder's lab is deservedly highly respected, and the Rhes explanation for striatal specificity of HD makes a lot of sense. However if in the absence of Rhes abnormal huntingtin forms aggregates in neurons more readily, why are these inclusions more prevalent in other parts of the brain and absent in striatal cells? I think there are still pieces of this puzzle to be discovered and fit together.--Douglas C Miller MD,PhDAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-5424255638293718915.post-81357959770746503962009-06-08T19:07:10.155-05:002009-06-08T19:07:10.155-05:00Interesting post Dr. MInteresting post Dr. MAdam Kinghttps://www.blogger.com/profile/12888814773419809679noreply@blogger.com